Reference Libraries

December 11, 2015

IN VITRO AND IN VIVO COMPARISON OF DERMAL IRRITANCY OF JET FUEL EXPOSURE USING EPIDERM (EPI-200) CULTURED HUMAN SKIN AND HAIRLESS RATS.

This study by researchers at the Schools of Pharmacy at Florida A&M University and Auburn University demonstrated that MatTek’s EpiDerm human skin tissue equivalent can be used as an alternative to animals in evaluating the dermal irritation potential of several... Read More

December 11, 2015

INHIBITORY EFFECTS OF Á-ARBUTIN ON MELANIN SYNTHESIS IN CULTURED HUMAN MELANOMA CELLS AND A THREE-DIMENSIONAL HUMAN SKIN MODEL.

We studied the inhibitory effects of 4-hydroxyphenyl á-glucopyranoside (á-arbutin) on melanogenesis in cultured human melanoma cells, HMV-II, and in a three-dimensional cultured human skin model. á-Arbutin showed no inhibitory effect on HMV-II cell growth at a concentration below 1.0 mM.... Read More

December 11, 2015

INITIAL IN VITRO SCREENING APPROACH TO INVESTIGATE THE POTENTIAL HEALTH AND ENVIRONMENTAL HAZARDS OF ENVIROX™ – A NANOPARTICULATE CERIUM OXIDE DIESEL FUEL ADDITIVE.

This study by scientists at Oxonica, Product Assessment & Regulatory Compliance, and SafePharm Laboratories Ltd. demonstrated that MatTek’s EpiDerm in vitro tissue model system can be used to determine the skin irritation potential of formulations containing nanoparticles. Nanotechnology is the... Read More

December 11, 2015

PREDICTIVE TESTING: UNDERSTANDING THE ROLE OF IN VITRO AND IN VIVO TESTING.

Understanding predictive in vitro testing of topically applied materials is especially important to the pharmacologist who works with the skin since this technology is applied for basic research and product development. This exhibit presents information and data on traditional and... Read More

December 11, 2015

THE USE OF MATTEK EPIDERMAL EQUIVALENTS FOR PREDICTION OF IRRITATION POTENTIAL.

The need exists for a rapid, accurate in vitro screening protocol, predictive for human skin irritation in response to topically applied products. The EPI-100, EpiDerm™ Human Skin Model System produced by MatTek Corp. (Ashland, MA) is being investigated for this... Read More

Reference Libraries

IN VITRO AND IN VIVO COMPARISON OF DERMAL IRRITANCY OF JET FUEL EXPOSURE USING EPIDERM (EPI-200) CULTURED HUMAN SKIN AND HAIRLESS RATS.

INHIBITORY EFFECTS OF Á-ARBUTIN ON MELANIN SYNTHESIS IN CULTURED HUMAN MELANOMA CELLS AND A THREE-DIMENSIONAL HUMAN SKIN MODEL.

INITIAL IN VITRO SCREENING APPROACH TO INVESTIGATE THE POTENTIAL HEALTH AND ENVIRONMENTAL HAZARDS OF ENVIROX™ – A NANOPARTICULATE CERIUM OXIDE DIESEL FUEL ADDITIVE.

PREDICTIVE TESTING: UNDERSTANDING THE ROLE OF IN VITRO AND IN VIVO TESTING.

THE USE OF MATTEK EPIDERMAL EQUIVALENTS FOR PREDICTION OF IRRITATION POTENTIAL.

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