Reference Libraries

December 11, 2015

DEVELOPMENT OF AN IN VITRO MODEL FOR THE PREDICTION OF SKIN IRRITATION POTENTIAL.

Cytokines important to the inflammatory cascade were measured both at the level of transcription and secreted protein, from skin equivalents topically exposed to a panel of relevant consumer products. The response of a full thickness model, consisting of both keratinocytes... Read More

December 11, 2015

THE USE OF STANDARDIZED HUMAN SKIN MODELS FOR CUTANEOUS PHARMACOTOXICOLOGY STUDIES.

Reconstructed skin and epidermis models are finding increasingly numerous applications in cosmetology and dermatology. In particular, they are currently employed to assess the tolerability and efficacy of raw materials and formulations, in conditions approaching those of normal use. Importantly, the... Read More

December 11, 2015

EVALUATION OF RECONSTRUCTED HUMAN EPIDERMIS KITS FOR THE IN VITRO ASSESSMENT OF COSMETIC SAFETY.

Reconstructed human epidermis is one of the most promising tools for in vitro evaluation of cosmetics. In recent years, their availability as kits offered to users practical models for the assessment of safety and efficacy of ingredients and finished products.... Read More

December 11, 2015

PRESENCE OF HYDROCORTISONE DRAMATICALLY AFFECTS CYTOKINE PRODUCTION FOLLOWING UV IRRADIATION IN 3-DIMENSIONAL SKIN MODEL EPIDERM.

Dating back to work originally done by Rheinwald and Green, hydrocortisone (HC) is commonly used in culture media for epithelial cells, especially keratinocytes. In the culture of EpiDerm™, a highly differentiated, three-dimensional model of the human epidermis, this additive is... Read More

December 11, 2015

IN VITRO AND IN VIVO COMPARISON OF DERMAL IRRITANCY OF JET FUEL EXPOSURE USING EPIDERM (EPI-200) CULTURED HUMAN SKIN AND HAIRLESS RATS.

This study by researchers at the Schools of Pharmacy at Florida A&M University and Auburn University demonstrated that MatTek’s EpiDerm human skin tissue equivalent can be used as an alternative to animals in evaluating the dermal irritation potential of several... Read More

Reference Libraries

DEVELOPMENT OF AN IN VITRO MODEL FOR THE PREDICTION OF SKIN IRRITATION POTENTIAL.

THE USE OF STANDARDIZED HUMAN SKIN MODELS FOR CUTANEOUS PHARMACOTOXICOLOGY STUDIES.

EVALUATION OF RECONSTRUCTED HUMAN EPIDERMIS KITS FOR THE IN VITRO ASSESSMENT OF COSMETIC SAFETY.

PRESENCE OF HYDROCORTISONE DRAMATICALLY AFFECTS CYTOKINE PRODUCTION FOLLOWING UV IRRADIATION IN 3-DIMENSIONAL SKIN MODEL EPIDERM.

IN VITRO AND IN VIVO COMPARISON OF DERMAL IRRITANCY OF JET FUEL EXPOSURE USING EPIDERM (EPI-200) CULTURED HUMAN SKIN AND HAIRLESS RATS.

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