Reference Libraries

December 11, 2015

PROGRAM TO REDUCE ANIMAL TESTING FOR EPA REGISTRATIONS OF ANTIMICROBIAL PRODUCTS.

This study by scientists at Proctor & Gamble, S.C. Johnson, the Institute for In Vitro Sciences (IIVS) and The Accord Group, in conjunction with the US EPA, documented how MatTek’s EpiDerm in vitro human skin tissue equivalent and EpiOcular in... Read More

December 11, 2015

INTER-AND INTRALABORATORY REPRODUCIBILITY OF A THREE DIMENSIONAL HUMAN EPIDERMAL MODEL – EPIDERM.

EpiDerm™ is a model of the human epidermis grown from normal human epidermal keratinocytes (foreskin-derived) seeded onto Millicell® CM (Millipore Corp., Bedford, MA) cell culture inserts. The inserts are placed at the air/culture medium interface allowing the cells to differentiate... Read More

December 11, 2015

MODULATION OF CYTOKINE MESSAGE IN THE EPIDERM IN VITRO SKIN MODEL FOLLOWING TREATMENT WITH CONTACT ALLERGENS AND SKIN IRRITANTS.

Previous studies have demonstrated that EpiDerm™ (MatTek Corporation) in vitro skin model constitutively expresses message for several cytokines (Limardi et al., 1996 JID 106, 939). The objective of research presented here is to assess the ability of irritants and contact... Read More

December 11, 2015

INTRA- AND INTERLABORATORY REPRODUCIBILITY (ET-50) OF EPIDERM, AN IN VITRO MODEL FOR DERMAL IRRITANCY TESTING.

An in vitro model of the human epidermis, EpiDerm™, cultured from normal human epidermal keratinocytes (NHEK), was introduced by MatTek Corporation in April 1993. Using highly controlled tissue culture techniques, weekly batches of EpiDerm are produced for dermal irritancy testing,... Read More

December 11, 2015

LIPID AND ULTRASTRUCTURAL CHARACTERIZATION OF A NEW EPIDERMAL MODEL SHOWS GOOD CORRESPONDENCE TO NORMAL HUMAN EPIDERMIS.

A model of the human epidermis, EpiDerm, based on neonatal foreskin-derived normal human epidermal keratinocytes (NHEK), has recently been characterized by scientists at the University of Iowa College of Dentistry in terms of stratum corneum (SC) lipids and ultrastructure. Cultured... Read More

Reference Libraries

PROGRAM TO REDUCE ANIMAL TESTING FOR EPA REGISTRATIONS OF ANTIMICROBIAL PRODUCTS.

INTER-AND INTRALABORATORY REPRODUCIBILITY OF A THREE DIMENSIONAL HUMAN EPIDERMAL MODEL – EPIDERM.

MODULATION OF CYTOKINE MESSAGE IN THE EPIDERM IN VITRO SKIN MODEL FOLLOWING TREATMENT WITH CONTACT ALLERGENS AND SKIN IRRITANTS.

INTRA- AND INTERLABORATORY REPRODUCIBILITY (ET-50) OF EPIDERM, AN IN VITRO MODEL FOR DERMAL IRRITANCY TESTING.

LIPID AND ULTRASTRUCTURAL CHARACTERIZATION OF A NEW EPIDERMAL MODEL SHOWS GOOD CORRESPONDENCE TO NORMAL HUMAN EPIDERMIS.

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