Reference Libraries

The goal of this study by researchers at Cosmital SA (Wella AG) and L’Oreal (Life Sciences Research, Centre) was to examine the concordance between human in vivo and in vitro skin irritation classifications of cosmetic products and to evaluate the... Read More

The aim of this study was to determine the reproducibility of data obtained from in vitro irritation testing using three industrial reconstructed human epidermis models, EpiDerm™, Episkin™ and SkinEthic(R), and one in-house model developed at Wella/Cosmital. A common protocol was... Read More

Analysis of epidermal proteins from irritant-treated in vitro epidermal models by proteomics is a promising approach to detect new markers of human skin irritation. These data provide a more comprehensive understanding of the mechanisms involved in the skin irritation response.... Read More

There is a need to investigate the mechanistic basis of the human skin irritation response if relevant in vitro test systems for the predictive identification of skin irritation are to be developed. The aim of this work was to identify... Read More