Reference Libraries

This study by scientists at Procter & Gamble demonstrated the ability to use MatTek’s EpiDerm in vitro human tissue equivalent as a preclinical test to confirm the mildness of prototype liquid antiperspirant formulations prior to beginning human clinical evaluations. Topical... Read More

This study by scientists at MatTek Corp. demonstrated that a modification of the common Skin Irritation protocol that extended the exposure time from 15 minutes to 60 minutes for MatTek’s EpiDerm in vitro human skin tissue model produced a significant... Read More

This study by researchers at Unilever’s Safety and Environmental Assurance Centre (SEAC) demonstrated how MatTek’s EpiDerm in vitro human skin tissue equivalent was used to identify a number of proteins that could be used as general markers for skin irritation.... Read More

This peer-reviewed, PubMed-indexed VIDEO technical article produced by scientists at MatTek Corp. and published in JoVE (Journal of Visualized Experiments) provides detailed instructions on how to perform the ECVAM-Validated EpiDerm Skin Irritation Test (SIT) Method, a stand-alone full replacement for... Read More

As stated in the “Conclusions” section, this study by scientists at the National Institute of Public Health (CZ), St. John’s Institute of Dermatology, Unilever SEAC, ZEBET, and MatTek Corp. demonstrated that in vitro 3D models derived from human skin cells... Read More