Reference Libraries

Determination of skin irritation potential is an international regulatory requirement to ensure safe handling, packaging, labeling and transport of chemicals and evaluation of cosmetics and household products. Recent REACH legislation and a ban on animal testing for cosmetics have heightened... Read More

This study by researchers at Unilever’s Safety and Environmental Assurance Centre (SEAC) demonstrated how MatTek’s EpiDerm in vitro human skin tissue equivalent was used to identify a number of proteins that could be used as general markers for skin irritation.... Read More

As stated in the “Conclusions” section, this study by scientists at the National Institute of Public Health (CZ), St. John’s Institute of Dermatology, Unilever SEAC, ZEBET, and MatTek Corp. demonstrated that in vitro 3D models derived from human skin cells... Read More

In autumn 2007, an international validation study was performed to evaluate the reproducibility and confirm the predictive ability of the EpiDerm Skin Irritation Test (SIT) method (1, 2). In November 2008, ECVAM endorsed the EpiDerm SIT as a full replacement... Read More