Reference Libraries

In 1996 and 1997, ECVAM supported a formal validation study on in vitro methods for predicting skin corrosivity. Two of the in vitro tests included in the study employed human skin models, the Skin ZK1350 and EPISKIN™ models. In the... Read More

The United States Department of Transportation recently granted an exemption for use of the in vitro Skin2 Model ZK1350 Corrosivity Assay as a replacement to rabbit skin corrosion testing for 6 chemical classes. The in vitro skin corrosion test is... Read More

This study by scientists at NIHS, Nihon Nohyaku Co., Ltd., Nippon Soda Co., Ltd., The Inst. Of Environmental Toxicology, Nippon Menard Cosmetic Co., Ltd., Sumitomo Chemical Co., Ltd., Kyoto University, and Tokyo University demonstrated that MatTek’s EpiDerm in vitro human... Read More

The purpose of this study, conducted by scientists at Unilever’s Safety and Environmental Assurance Centre, was to assess the in-house performance of the EpiDerm and EPISKIN corrosivity tests using materials of known corrosive potential (six corrosives and six non-corrosives), as... Read More

Scientists from The Procter and Gamble Company investigated the feasibility of an in-vitro skin corrosion test method using commercially available human skin cultures. Skin2 from Advanced Tissue Sciences and EpiDerm from MatTek were evaluated for their responses to 24 corrosive... Read More