Reference Libraries

Classification and labeling of products with extreme pH values (62 or P11.5) is addressed in chemicals legislation. Following determination of pH and alkaline/acid reserve, additional in vitro tests are needed, especially to substantiate results less than corrosive. However, only limited... Read More

This study by researchers at Unilever’s Safety and Environmental Assurance Centre (SEAC) demonstrated how MatTek’s EpiDerm in vitro human skin tissue equivalent was used to identify a number of proteins that could be used as general markers for skin irritation.... Read More

Arachidonic acid (AA), a precursor of pro-inflammatory mediators, and its glycerin ester, glyceryl arachidonate (GA), are reportedly used in cosmetic products. In vitro skin penetration of AA and GA and GA’s ester hydrolysis was determined in flow-through diffusion cells. AA... Read More

A major milestone for in vitro skin irritation testing was achieved with the recent release of the Statement on the Validity of In-Vitro Tests for Skin Irritation by the European Centre for the Validation of Alternative Methods (ECVAM) Scientific Advisory... Read More