Reference Libraries

December 11, 2015

EVALUATION OF A TISSUE ENGINEERED HUMAN SKIN EPIDERM 3-D CULTURE AS A MODEL TO STUDY IRRITATION AFTER JET FUEL EXPOSURE.

This study by researchers at Florida A&M University demonstrated that MatTek’s EpiDerm in vitro human skin tissue equivalent is a “valuable model to evaluate the skin irritation potential of jet fuels and hydrocarbon chemicals”. The purpose of the present study... Read More

December 11, 2015

IN VITRO AND HUMAN TESTING STRATEGIES FOR SKIN IRRITATION.

Prior to the manufacture, transport, and marketing of chemicals or products, it is critical to assess their potential for skin toxicity (corrosion or irritation), thereby protecting the worker and consumer from adverse skin effects due to intended or accidental skin... Read More

December 11, 2015

STRATEGIES FOR THE ASSESSMENT OF ACUTE SKIN IRRITATION POTENTIAL.

The manufacture, transport, and marketing of chemicals and finished products requires the prior toxicologic evaluation and assessment of skin reactivity (corrosion and irritation) that may result from intended or accidental skin exposure. Procedures for the skin testing of new chemicals... Read More

December 11, 2015

LONG TERM REPRODUCIBILITY OF EPIDERM, AN EPIDERMAL MODEL FOR DERMAL TESTING AND RESEARCH.

This technical reference summarizes MatTek’s 10-plus YEAR EpiDerm tissue reproducibility data. Long-term reproducibility is important not only to MatTek Customers, but also to European (ECVAM) and US (ICCVAM) regulators. Regulators constantly stress the need for superior reproducibility of in vitro... Read More

December 11, 2015

DEVELOPMENT OF AN IN VITRO CORROSION/IRRITATION PREDICTION ASSAY USING THE EPIDERM™ SKIN MODEL.

This study by scientists at Covance Laboratories and the University of York demonstrated that MatTek’s EpiDerm in vitro human skin tissue equivalent can be used to accurately predict the dermal corrosivity and skin irritation potential of 12 test chemicals. A... Read More