Reference Libraries

December 11, 2015

PREVALIDATION OF TESTS FOR PREDICTING SKIN CORROSIVITY AND PHOTOTOXICITY USING AN IN VITRO MODEL OF HUMAN EPIDERMIS.

Tests for prediction of skin corrosivity and dermal phototoxicity using the model EpiDerm™ were evaluated at ZEBET in a prevalidation study funded by the European Centre for the Validation of Alternative Methods (ECVAM). The study comprised an interlaboratory method transfer,... Read More

December 11, 2015

ENSURING QUALITY OF IN VITRO ALTERNATIVE TEST METHODS: ISSUES AND ANSWERS.

This report by scientists at the US EPA, the US Consumer Product Safety Commission, the European Center for the Validation of Alternative Methods (ECVAM) and the Institute for In Vitro Sciences (IIVS) discussed the importance of having specific quality control... Read More

December 11, 2015

REGULATORY REQUIREMENTS FOR IN VITRO SYSTEMS TO MEET PERFORMANCE STANDARDS OVER TIME AS WELL AS DURING VALIDATION.

This technical poster by scientists at MatTek Corp. summarized 12-PLUS YEARS (1996-2007) of commercial production QC data for MatTek’s EpiDerm and EpiOcular in vitro human tissue equivalents, and how that data addresses regulatory concerns regarding performance standards of alternative in... Read More

December 11, 2015

EVALUATION OF A TISSUE ENGINEERED HUMAN SKIN EPIDERM 3-D CULTURE AS A MODEL TO STUDY IRRITATION AFTER JET FUEL EXPOSURE.

This study by researchers at Florida A&M University demonstrated that MatTek’s EpiDerm in vitro human skin tissue equivalent is a “valuable model to evaluate the skin irritation potential of jet fuels and hydrocarbon chemicals”. The purpose of the present study... Read More

December 11, 2015

STRATEGIES FOR THE ASSESSMENT OF ACUTE SKIN IRRITATION POTENTIAL.

The manufacture, transport, and marketing of chemicals and finished products requires the prior toxicologic evaluation and assessment of skin reactivity (corrosion and irritation) that may result from intended or accidental skin exposure. Procedures for the skin testing of new chemicals... Read More

Reference Libraries

PREVALIDATION OF TESTS FOR PREDICTING SKIN CORROSIVITY AND PHOTOTOXICITY USING AN IN VITRO MODEL OF HUMAN EPIDERMIS.

ENSURING QUALITY OF IN VITRO ALTERNATIVE TEST METHODS: ISSUES AND ANSWERS.

REGULATORY REQUIREMENTS FOR IN VITRO SYSTEMS TO MEET PERFORMANCE STANDARDS OVER TIME AS WELL AS DURING VALIDATION.

EVALUATION OF A TISSUE ENGINEERED HUMAN SKIN EPIDERM 3-D CULTURE AS A MODEL TO STUDY IRRITATION AFTER JET FUEL EXPOSURE.

STRATEGIES FOR THE ASSESSMENT OF ACUTE SKIN IRRITATION POTENTIAL.

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