Reference Libraries

December 11, 2015

A TRIPLE CELL CO-CULTURE MODEL OF THE AIR-BLOOD BARRIER RECONSTRUCTED FROM PRIMARY HUMAN CELLS.

Reliable in vitro human models for investigating airway toxicity are needed to advance Tox21 efforts to replace animal testing with human-based model systems. In vitro airway models based on primary human cells have been described, however, models based on animal... Read More

December 11, 2015

RETROSPECTIVE ANALYSIS OF THE EPIDERM 3-MINUTE PREDICTION MODEL FOR ASSESSMENT OF GHS SKIN CORROSION PACKING GROUP SUB-CATEGORY 1A.

OECD has adopted several ECVAM-validated reconstructed human skin models (EpiDerm and EPISKIN/SkinEthic) for testing skin corrosion as OECD TG 431(1). However, OECD TG 431 does not satisfy international (GHS) labeling guidelines for transport of dangerous goods. GHS package labeling guidelines... Read More

December 11, 2015

APPLICATIONS OF THE PHYTOMEDICINE ECHINACEA PURPUREA (PURPLE CONEFLOWER) IN INFECTIOUS DISEASES.

Extracts of Echinacea purpurea (EP, purple coneflower) have been used traditionally in North America for the treatment of various types of infections and wounds, and they have become very popular herbal medicines globally. Recent studies have revealed that certain standardized... Read More

December 11, 2015

IN VITRO SKIN CORROSION TEST: LONG TERM REPRODUCIBILITY AND RELIABILITY FOR A REGULATORY ACCEPTED METHOD.

This study by scientists at the Institute for In Vitro Sciences (IIVS) and MatTek Corp. demonstrated the long term reproducibility and reliability of MatTek’s EpiDerm tissue model and the EpiDerm Dermal Corrosion assay protocol, as required by regulators. The EpiDerm... Read More

December 11, 2015

USE OF THE EPIAIRWAY MODEL FOR CHARACTERIZING LONG-TERM HOST-PATHOGEN INTERACTIONS.

Nontypeable Haemophilus influenzae (NTHi) are human-adapted Gram-negative bacteria that can cause recurrent and chronic infections of the respiratory mucosa 1; 2. To study the mechanisms by which these organisms survive on and inside respiratory tissues, a model in which successful... Read More

Reference Libraries

A TRIPLE CELL CO-CULTURE MODEL OF THE AIR-BLOOD BARRIER RECONSTRUCTED FROM PRIMARY HUMAN CELLS.

RETROSPECTIVE ANALYSIS OF THE EPIDERM 3-MINUTE PREDICTION MODEL FOR ASSESSMENT OF GHS SKIN CORROSION PACKING GROUP SUB-CATEGORY 1A.

APPLICATIONS OF THE PHYTOMEDICINE ECHINACEA PURPUREA (PURPLE CONEFLOWER) IN INFECTIOUS DISEASES.

IN VITRO SKIN CORROSION TEST: LONG TERM REPRODUCIBILITY AND RELIABILITY FOR A REGULATORY ACCEPTED METHOD.

USE OF THE EPIAIRWAY MODEL FOR CHARACTERIZING LONG-TERM HOST-PATHOGEN INTERACTIONS.

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