PERCUTANEOUS PERMEATION OF ZINC FROM NON-WOVEN FABRICS IMPREGNATED WITH ZINC SULFATE MONOHYDRATE FORMULATIONS USING EPIDERM™.

Zinc sulfate monohydrate is a widely used agent in the pharmaceutical industry. It can be applied on the skin in the form of a solution, ointment, or lotion, and recently in the form of non-woven fabrics impregnated with zinc sulfate monohydrate formulations. Topical zinc preparations have been found to accelerate wound healing and relieve chronic skin ulcers. The main goal of this study was to evaluate the permeation of zinc from non-woven fabrics impregnated with different formulations containing 1% zinc sulfate monohydrate (oily bases, aqueous lotions, and emulsion formulations) through EpiDerm™. Oily bases contained in addition to other ingredients, phospholipid SV, phospholipid CDM, and Monamid 150-IS. Aqueous lotions contained ahcovel. water, and serocin. Emulsions contained ahcovel, water, and serocin, brazil nut oil or crosilk.

Dermal absorption, Dermal penetration, Dermal permeation, EpiDerm, Non-woven fabrics, Percutaneous absorption, Percutaneous penetration, Skin ulcers, Topical zinc preparations, Transdermal, Wound healing, Zinc sulfate monohydrate