View our list of posters being presented at the 9th World Congress meeting in Prague, Czech Republic, and request copies at any time. Electronic copies of the posters will be sent via email after the meeting has concluded. Thank you for your requests!
In vitro human alveolar tissue model for pulmonary drug delivery and toxicology applications
P. J. Hayden, G. R. Jackson, J. Oldach, C. Mankus, S. Ayehunie, M. Klausner, H. Kandarova
Research & Development, MatTek Corporation, Ashland, USA
phayden@mattek.com
I-4-738
Importance of reproducibility demonstration of the bio-engineered tissue models used for in vitro toxicity testing purposes
S. Letasiova1, M. Bachelor2, H. Kandarova1, K. Sebova1, P. Kearney2, M. Klausner2
1 MatTek In Vitro Life Science Laboratories, IVLSL, Bratislava, Slovakia
2 MatTek Corporation, MatTek Corporation, Ashland, MA, USA
sletasiova@mattek.com
I-4-776
Reconstructed 3-D human small intestinal tissue to assess drug safety, inflammation, and restitution
S. Ayehunie, Z.Stevens, T.Landry, M. Klausner , P. Hayden
R &D, MatTek Corporation, Ashland, USA
phayden@mattek.com
I-4-778
Optimization of an eye irritation assay for solid materials for hazard identification and labelling of chemicals
Y. Kaluzhny1, H. Kandarova2, L. d’Argembeau-Thornton 1, J. De Luca 1, P. Hayden1, A. Hunter1, T. Truong1, K. Klausner1
1 Tissue engineering, MatTek Corporation, Ashland, MA, USA
2 Tissue engineering, MatTek In Vitro Life Science, Bratislava, Slovakia
hkandarova@mattek.com
II-4-398
Use of ECVAM validated EpiDerm skin corrosion test (EpiDerm SCT) for sub-categorization according to the UN GHS
H. Kandarova1, S. Letasiova1, T. Milasova1, P. Hayden2, M. Klausner1
1 MatTek In Vitro Life Science Laboratories, IVLSL, Bratislava, Slovakia
2 MatTek Corporation, MatTek Corporation, Ashland, MA, USA
hkandarova@mattek.com
II-10-868
Reconstructed Human Epidermis Test Methods for Skin Corrosion Endpoint: How Can Changes in Prediction Models Improve Final Predictions?
B. Desprez1, J. Barroso1, C. Griesinger1, H. Kandarova2, N. Alépée3, H. Fuchs4
1 EURL ECVAM / Systems Toxicology Unit – IHCP, European Commission Joint Research Centre, Ispra, Italy
2 MatTek In Vitro Life Science Laboratories, Bratislava, Slovakia
3 Department of Predictive Biological Methods and Models, L’Oréal Research & Innovation, Aulnay Sous Bois, France
4 CellSystems® Biotechnologie Vertrieb GmbH, Troisdor, Germany
bertrand.desprez@ec.europa.eu
II-10-936
Development of improved skin sensitization assays based on 3D reconstructed human epidermal equivalents and secreted luciferase reporter activity
P. J. Hayden1, M. Miyazawa2, P. Lei3, C. Mankus2, O. Takenouchi2, K. Saito2, G. R. Jackson1, S. T. Andreadis3, Y. Ohmiya4, H. Sakaguchi2
1 Research, MatTek Corporation, Ashland, USA
2 Research, Kao Corporation, Tochigi, Japan
3 Tissue Engineering, University at Buffalo-The State University of New York, Buffalo, USA
4 Research, Advanced Industrial Science and Technology, Tokyo, Japan
phayden@mattek.com
II-12-716
IL-18 secretion as a marker for identification of contact sensitizers in the EpiDerm™ in vitro human skin model
J. Oldach, S. Letasiova, H. Kandarova, M. Klausner, P. J. Hayden
Research, MatTek Corporation, Ashland, USA
phayden@mattek.com
II-12-742
Co-culture assay for the identification and investigation of dermal sensitizers (epi-dc)
G. DeGeorge1, M. Troese1, L. Pratt 1, M. Piehl1, P. Hayden2, S. Ayehunie2
1 IVT, MB Research Labs, Spinnerstown, PA, USA
2 1, MatTek Corporation, Ashland, MA, USA
degeorge@mbresearch.com
II-12-833
Application of in vitro skin models for cosmetic product efficacy: UV protection, skin lightening, skin hydration and anti-aging
M. Bachelor, A. Armento, B. Breyfogle, G. Stolper, J. Oldach, M. Klausner, P.J. Hayden
Research & Development, MatTek, Ashland, USA
mklausner@mattek.com
VI-1-840
Evaluation of serum growth factors in wound healing using a full-thickness in vitro human skin model
M. Bachelor, A. Armento, G. Stolper, J. Oldach, M. Li, M. Klausner, P.J. Hayden
Research, MatTek Corporation, Ashland, USA
mklausner@mattek.com
VI-5-822
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Assessment of phototoxic potential of topically applied substances and formulations using 3D reconstructed human skin models
H. Kandarova1, D. Jírová2, K. Kejlová2, M. Liebsch3
1 MatTek In Vitro Life Science Laboratories, IVLSL, Bratislava, Slovakia
2 Centre of Toxicology and Health Safety, National Institute of Public Health, Prague, Czech Republic
3 ZEBET at the BfR, Federal Institute for Risk Assessment (retired), Berlin, Germany
hkandarova@mattek.com
II-4b-777
Date: Monday 25 August 2014
Time: 10:15–12:15
Room: Congress Hall II
Responses of in vitro asthmatic human airway epithelial cultures to rhinovirus and poly(I:C)
J. Bai1, S. L. Smock1, G. R. Jackson2, K. D. MacIsaac1, Y. Huang1, M. Crackower1, Y. Ma1, J. A. Klappenbach1, S. E. Alves1, P. J. Hayden2
1 Research Laboratories, Merck, Boston, USA
2 Research, MatTek Corporation, Ashland, USA
phayden@mattek.com
VI-1a-740
Date: Monday 25 August 2014
Time: 1:30–3:00
Room: Palmovka + Rokoska + Hercovka
An In vitro reconstructed psoriasis tissue model for evaluation of drug therapeutics
M. Klausner, C. Hedin, A. Cataldo, M. Spratt, P. Hayden, S. Ayehunie
R&D, MatTek Corporation, Ashland, USA
mklausner@mattek.com
VI-1c-782
Date: Wednesday 27 August 2014
Time: 10:00–12:00
Room: Karlín II + III
Application of in vitro human airway models for toxicology,drug delivery and disease modelling
P. Hayden, G.R. Jackson, A. Su, C. Mankus, J. Oldach, S. Ayehunie, H. Kandarova, M. Klausner
Research & Development, MatTek Corporation, Ashland, USA
phayden@mattek.com
VI-5-864
Date: Monday 25 August 2014
Time: 10:15–12:15
Room: Vienna + Roma
Potential and limitations of reconstructed human skin models in assessing pharmaceutical formulations
H. Kandarova
MatTek In Vitro Life Science Laboratories, Bratislava, Slovakia
hkandarova@mattek.com
VI-5-933
Date: Monday 25 August 2014
Time: 10:15–12:15
Room: Vienna + Roma
