Reference Libraries

October 5, 2020

PT150 is a modulator of glucocorticoid and androgen receptors with antiviral activity against SARS-CoV-2

PT150 is a clinical stage molecule, taken orally, with a strong safety profile having completed Phase 1 and Phase 2 clinical trials for its original use as an antidepressant. It has an active IND for COVID-19. Antiviral activities have been... Read More

October 5, 2020

Evaluation of phototoxicity of tattoo pigments using the 3 T3 neutral red uptake phototoxicity test and a 3D human reconstructed skin model

Phototoxicity due to dermally impregnated compounds exposed to ultraviolet radiation is associated with skin inﬂammation. The phototoxicity potential of active substances applied to the skin should be evaluated. Pigments are widely used for tattoos, and hypersensitivity reactions, such as photoallergic... Read More

October 5, 2020

Endogenous acid ceramidase protects epithelial cells from Porphyromonas gingivalis-induced inflammation in vitro

Ceramidases are a group of enzymes that degrade pro-inflammatory ceramide by cleaving a fatty acid to form anti-inflammatory sphingosine lipid. Thus far, acid, neutral and alkaline ceramidase isozymes have been described. However, the expression patterns of ceramidase isoforms as well... Read More

October 5, 2020

Intense THz pulses cause H2AX phosphorylation and activate DNA damage response in human skin tissue

Recent emergence and growing use of terahertz (11-Iz) radiation for medical imaging and public security screening raise questions on reasonable levels of exposure and health consequences of this form of electromagnetic radiation. In particular, picosecond-duration 11-Iz pulses have shown promise... Read More

October 1, 2020

Anti-Aging Potentials of Methylene Blue for Human Skin Longevity

Oxidative stress is the major cause of skin aging that includes wrinkles, pigmentation, and weakened wound healing ability. Application of antioxidants in skin care is well accepted as an effective approach to delay the skin aging process. Methylene blue (MB),... Read More

Reference Libraries

PT150 is a modulator of glucocorticoid and androgen receptors with antiviral activity against SARS-CoV-2

Evaluation of phototoxicity of tattoo pigments using the 3 T3 neutral red uptake phototoxicity test and a 3D human reconstructed skin model

Endogenous acid ceramidase protects epithelial cells from Porphyromonas gingivalis-induced inflammation in vitro

Intense THz pulses cause H2AX phosphorylation and activate DNA damage response in human skin tissue

Anti-Aging Potentials of Methylene Blue for Human Skin Longevity

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